jquip : Smaller, Lighter, Faster, more modular jQuery - include only the parts you want! Don't use it, Don't include it.
impress.js : It's a presentation framework based on the power of CSS3 transforms and transitions in modern browsers and inspired by the idea behind prezi.com
RequireJS : RequireJS is a JavaScript file and module loader. It is optimized for in-browser use, but it can be used in other JavaScript environments, like Rhino ...
xui.js : A super micro tiny DOM library for authoring HTML5 mobile web applications.
jsmad : jsmad is a pure javascript MP3 decoder, based on libmad, with an ID3 decoder written from scratch.
Sammy is a tiny javascript framework built on top of jQuery, It's RESTful Evented Javascript.