SoundManager 2 : Using HTML5 and Flash, SoundManager 2 provides reliable cross-platform audio under a single JavaScript API.
meSpeak.js : meSpeak.js (modulary enhanced speak.js) is a 100% client-side JavaScript text-to-speech library
howler.js : howler.js is an audio library for the modern web. It defaults to Web Audio API and falls back to HTML5 Audio.
dancer.js : dancer.js is a high-level audio API, usable with both Mozilla's Audio Data API and Webkit's Web Audio API with flash fallback, designed to make sweet ...
jsfx : This is a javascript library (with frontend) for sound effect generation.
howler.js is an audio library for the modern web. It defaults to Web Audio API and falls back to HTML5 Audio. This makes working with audio in JavaScript easy and reliable across all platforms.