SoundManager 2 : Using HTML5 and Flash, SoundManager 2 provides reliable cross-platform audio under a single JavaScript API.
meSing.js : meSing.js is a JavaScript singing synthesis library that uses the Web Audio API's DSP capabilities in conjunction with the meSpeak.js speech synthesis...
Band.js : An interface for the Web Audio API that supports rhythms, multiple instruments, repeating sections, and complex time signatures.
howler.js : howler.js is an audio library for the modern web. It defaults to Web Audio API and falls back to HTML5 Audio.
jsfx : This is a javascript library (with frontend) for sound effect generation.
howler.js is an audio library for the modern web. It defaults to Web Audio API and falls back to HTML5 Audio. This makes working with audio in JavaScript easy and reliable across all platforms.